face contouring is a medical procedure that aims to modify the structure of bones, fat tissue, and facial muscles through surgical and non-surgical approaches. [1]This procedure can be performed for medical reasons or simply for aesthetic purposes. Aesthetically, face contouring The aim of this procedure is to improve the proportions and symmetry of the face or create a more youthful appearance. 

For individuals experiencing decreased elasticity or reduced facial volume, stem cell therapy offers the potential to help restore plumpness to areas such as the cheeks, under-eye area, and jawline, resulting in a more youthful and refreshed appearance. [2]. Unlike aesthetic procedures, facial contouring procedures performed for medical purposes are more focused on reconstructing or repairing facial structures caused by trauma, disease, or birth defects. In some cases, facial contouring procedures are performed to restore mobility, such as improving chewing function. [2]. 

In facial contouring procedures, several components are used. One of them is stem cells. obtained from fat tissue and umbilical cord tissue, and the utilization of fat that is processed into stromal vascular fraction (SVF). The integration of these components aims to correct abnormalities in facial structure and increase the regeneration of skin cells in the body which are processed into [3,4]. 

This therapy is expected to provide more stable long-term results, thus minimizing the frequency of future corrective procedures. This advantage is supported by the characteristics of stem cells that can help achieve optimal results in various aspects, including:

1. Fat Regeneration: Stem cell therapy can help ensure that fat tissue stays alive and survives by forming new blood vessels and turning into fat cells[3].
2. Improves Skin Quality: Stem cell therapy can release certain molecules to help repair damaged skin layers and increase collagen and elastin production.[3].
3. Long-lasting results: By using stem cells, the body will be easier to integrate because stem cells are not foreign objects but biological material.[3].

Currently, stem cell therapy services are available in reconstructive and aesthetic plastic surgery cases, particularly facial contouring procedures. can be done based on Decree of the Minister of Health of the Republic of Indonesia Number HK.01.07/MENKES/1200/2025 concerning Guidelines for the Implementation of Cell and/or Stem Cell Therapy Services in the Field of Reconstructive and Aesthetic Plastic Surgery.

In line with these regulations, ProSTEM provides high-quality stem cells produced in facilities certified by Good Manufacturing Practices (GMP) and licensed by the Ministry of Health. This demonstrates ProSTEM's full dedication to maintaining quality and safety standards. We ensure that every therapy service provided is safe, effective, and complies with medical regulations for patient safety. For more information regarding stem cell therapy services related to facial contouring procedures, please contact us via WhatsApp on this website.

References

1. Moradi, A., Montes, J. R., Humphrey, S., Grunebaum, L. D., Bertossi, D., Dimitrijevic, E., & Sangha, S. (2024). A unified approach to facial contours and volume correction: The role of the cheek and the chin. Plastic and Reconstructive Surgery – Global Open, 12(10), e6219. https://doi.org/10.1097/GOX.0000000000006219
2. Brito, G. C., De Moraes, M., Faverani, L., & Olate, S. (2025). Facial contouring in orthognathic surgery: The role of facial implants. Craniomaxillofacial Trauma & Reconstruction, 19(1), 2. https://doi.org/10.3390/cmtr19010002
3. Bourne, D. A., Egro, F. M., Bliley, J., James, I., Haas, G. L., Meyer, E. M., Donnenberg, V., Donnenberg, A. D., Branstetter, B., Coleman, S., & Rubin, J. P. (2023). Stem cell therapy enriched fat grafting for the reconstruction of craniofacial deficits. Plastic & Reconstructive Surgery Global Open, 11(6), e5056. https://doi.org/10.1097/gox.0000000000005056
4. Rehman, A., Nigam, A., Laino, L., Russo, D., Todisco, C., Esposito, G., Svolacchia, F., Giuzio, F., Desiderio, V., & Ferraro, G. (2023). Mesenchymal stem cells in Soft Tissue Regenerative Medicine: A Comprehensive review. Medicina, 59(8), 1449. https://doi.org/10.3390/medicina59081449